While the Environmental Genome Project does not seek to assign allele frequencies, we are aware of the importance of accurate allele frequency estimates for future epidemiologic studies and the large sample sizes such estimates will require. – Samuel Wilson

The infrastructure for linking environmental health and public health is not working as well as it should. – Samuel Wilson

It is important to consider whether the sample size selected by the Environmental Genome Project will provide sufficient power to discover most alleles relevant to gene-environment interactions. – Samuel Wilson