One must never assume that a character is sympathetic because of either the actor playing them or the fact that theyre a lead. I think thats a recipe for failure, actually, because if they become unsympathetic, you lose your audience. – Melissa Rosenberg
Human destiny is bound to remain a gamble, because at some unpredictable time and in some unforeseeable manner nature will strike back. – Rene Dubos, Mirage of Health, 1959