It is important to consider whether the sample size selected by the Environmental Genome Project will provide sufficient power to discover most alleles relevant to gene-environment interactions. – Samuel Wilson

While the Environmental Genome Project does not seek to assign allele frequencies, we are aware of the importance of accurate allele frequency estimates for future epidemiologic studies and the large sample sizes such estimates will require. – Samuel Wilson

One of the responsibilities faced by the Environmental Genome Project is to provide the science base upon which society can make better informed risk management decisions. – Samuel Wilson